BSC 315 Lecture Notes - Lecture 8: Spermatogonium, Sister Chromatids, Oogenesis

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Occurs only in germ line, during gametogenesis. Outcome (goal): diploid meiocytes produce haploid daughter cells: non-chromosome mechanisms similar to mitosis, chromosome mechanisms are distinct. Prophase i: each chromosome contains 2 chromatids. Chromosomes condense, homologs pair and undergo crossing over (homologs exchange segments) Anaphase i: chromatids do not split; homologs separate and segregate. Telophase i: each daughter cell contains 2 chromosomes (n = 1; haploid). Prophase ii: 2 haploid cells; each chromosome contains 2 chromatids. Anaphase ii: chromosomes split into 2 chromatids; chromatids segregate. Telophase/result: 4 haploid cells; each chromosome contains 1 chromatid. Segregation explained: behavior of chromosomes parallels behavior of genes: diploid meiocytes to haploid gametes, equal representation of each homologous chromosome in gametes, fertilization restores diploid chromosome number. Independent assortment: chromosome segregation parallels segregation of alleles: each meiosis produces either a b and a b or a b and a b gametes depending on segregation at meiosis i, each type of meiotic division is equally probable.

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