BSC 431 Lecture Notes - Lecture 36: Oral Mucosa, Phagocytosis, Respiratory Tract

• School: University of Alabama
• Department: Biological Sciences
• Course: BSC 431
• Professor: Julie Olson

Document Summary

Death- host cell functions are shut down, lysis. Latent infection- the virus survives in an inactive state to be reactivated later (cid:1) (cid:1) (cid:1) (cid:1) (cid:1) (cid:1) (cid:1) (cid:1) (cid:1) Chronic slow infection- slow spread of infection over many years. Virus induced cell-cell fusion: syncytia- huge virus factories. Vertical spread of the genome to daughter cells. Large numbers of progeny- high chance of mutation in a short time. Dna viruses more genetically stable than rna viruses because there are error correction mechanisms for dna but not for rna. Some rna viruses tolerate very little variation in nature; variant cells do not compete well w/ wildtype so become absent in the population (cid:1) (cid:1) (cid:1) (cid:1) (cid:1) (cid:1) (cid:1) (cid:1) (cid:1) (cid:1) (cid:1) (cid:1) (cid:1) (cid:1) Common in dna viruses & rna viruses w/ a dna phase (retroviruses) Rare in other rna viruses (no host enzymes for rna recombination??) Recombination occurs in all dna viruses that have been studied.