NHM 101 Lecture Notes - Lecture 20: Methionine, Thiamine, Folic Acid

• School: University of Alabama
• Department: Food Science
• Course: NHM 101
• Professor: Rusung Tan

Document Summary

Participates in conversion of pyruvate to acetyl coa. Beriberi: damage to nervous system, heart, and muscle weakness. Both fmn and fad can accept and donate hydrogen atoms. Causes inflammation of mouth, eyes, skin and gi tract. Pellagra: four d"s diarrhea, dermatitis, dementia, death. Niacin flush: large dose of nicotinic acid: dilates capillaries and causes a tingling sensation. Metabolism-as a coenzyme in gluconeogenesis, fatty acid synthesis, and breakdown of amino acids and fatty acids. High consumption of raw egg whites (2 dozen or more per day) may cause deficiency. Symptoms of deficiency: depression, lethargy, red, scaly rash, hair loss. Part of coenzyme a used in energy metabolism. Synthesis of lipids, neurotransmitters, steroid hormones, and hemoglobin. Symptoms include: fatigue, gi distress, neurological disturbances. Coenzyme involved in amino acid and fatty acid metabolism. Results in diminished synthesis of key neurotransmitters and accumulation of abnormal compounds in the brain. Coenzyme involved in metabolism: helps with conversion of vit b12 to a coenzyme form.