PGY 300 Lecture Notes - Lecture 10: Peristalsis, Bradycardia, Achalasia
Document Summary
Adrenal medulla epinephrine vagus nerve ach brain stem ne amygdala: somatic neuromuscular junction (recall, each fiber synapses, localized, fast reaction, autonomic postganglionic synapse, varicosities: series of synapses, diffuse around looking for receptors a. i) contain nt and mitochondria, no cleft c) Large area, slow acting and long duration: reciprocal innervation in the ans, can produce excitation or inhibition, antagonism is on the same muscle but by pns and sns, enteric system a) Innervates the gut: myenteric plexus (auerbach) motility b. i) controls circular and longitudinal muscles b. ii) ach excitatory, no inhibitory (in the aboral direction), amplified by vip b. iii) Sensory neurons: stretch and tension: submucosal (meissner) plexus secretion and contraction of muscularis mucosa c. i) sensory neurons: chemical receptors sensitive to luminal content (acid, glucose, fats and. Aa: can function on its own, controlled largely from pns (vagus), activates nicotinic receptors and ens acts as postganglionic nerve f)