PMY 302 Lecture Notes - Lecture 10: Peroxisome Proliferator-Activated Receptor, Testosterone Cypionate, Pubic Hair

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30 Jan 2015
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Endocrine system: secrete hormones directly into the circulatory system to be carries toward a distant target organ. Endocrine pharmacology: study of drugs that are hormones, hormone derivatives, modify the synthesis, action of normally secreted hormones. Endocrine glands and hormones: hypothalamic pituitary control. Thyroid gland thyroid hormone: parathyroid pth, adrenal gland aldosterone, cortisol, androgens, pancreas insulin, ovary estrogens and progesterone. Hormones: regulatory substance produced in an organism, classified into 3 groups. Clinical pharmacology hormones: replacement therapies hormone deficiencies. Growth hormone, thyroid hormone, insulins, glucocorticoids, mineralocorticoids, pth1- 34, fsh-lh, estrogens, testosterone, oxytocin, vasopressin: pharmacologic doses suppress normal pathways. Coc (progestins/estrogens), gnrh (leuprolide: antagonize natural hormones or their production. Tamoxifen, aromatase inhibitors, bicalutamide, gnrh antagonist, octreotide, methimazole: anti-inflammatory effects. Hypothalamic and pituitary endocrinology: end organ relationship. Inhibitory control by dopamine: suppression of hyperprolactinemia. Positive feed forward and negative feedback regulation: gnrh is released by the hypothalamus and acts on the anterior pituitary to stimulate release of.

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