BSCI 105 Lecture Notes - Lecture 5: C-Terminus, N-Terminus, Alpha Helix

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Proteins move things around: actin, myosin. Amino acids: 20 amino acids in proteins, sidechains can be nonpolar and hydrophobic because they lack electronegative atoms. Aliphatic has only hydrogen and carbon: completely saturated. Aromatic has benzene rings: sidechains can be polar and hydrophilic. Have nitrogen or hydrogen: sidechains can be ionic. Acids or bases: nonpolar, polar, ionic. Synthesizing a protein: amino acids are linked by peptide bonds. Peptide bonds are formed by a dehydration reaction. Dehydration links the carboxyl group of one amino acid to the amino group of the next amino acid. Every protein has an amino terminus with a free amino acid and a carboxyl terminus with a free carboxyl group: proteins are synthesized from their amino terminus to their carboxyl terminus. Secondary structures: hold alpha-helicies and pleated sheets, helt together by hydrogen bonds between c=o and n-h groups, h-bonds in aplpha helicies are within a single strand, h-bonds in pleated sheets are between strands.

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