BSCI 105 Lecture Notes - Lecture 16: Guanine, Phosphorylation, Multiprotein Complex

• School: University of Maryland
• Department: Biological Sciences Program
• Course: BSCI 105
• Professor: Keller

Document Summary

Methionine: in prokaryotic cells, proteins to be secreted to the outside of the cell are translated at the plasma membrane. Region of dna including instructions to make something (i. e. ; coding regions) Contains information to make rna: where rna starts and stops, regulatory information. Synthesis of rna from dna: nucleic acid to nucleic acid, dna is the template. Rna made is a complement of dna. Enzyme: rna polymerase: helicase and polymerase activity, does not require a primer, prokaryotes. One type that transcribes all rnas: eukaryotes. Rna polymerase i rrna ribosomal rna. Rna polymerase iii trna (transfer rna) and other small rnas. Mechanism of transcription: base pairing, phosphodiester bonds. Upstream of the initiation site (where transcription begins) Proteins bind first, then recruit rna pol ii. Specific transcription factors upstream regulatory transcription factors: positive activators, enhancers, negative repressors, elongation. Elongation is the same for both prokaryotes and eukaryotes: termination. Product is pre-mrna that needs to be processed further.