BSCI 105 Lecture Notes - Lecture 12: Spindle Apparatus, Sister Chromatids, Chromatid
Document Summary
The cell as the fundamental unit of life. Cell division: growth and regulation of the cell cycle. Production of new cells from existing cells. One cell grows and divides into two daughter cells. Binary fission: cell wall/membrane, cytoplasm, ribosomes, nucleoid body. Chromosomal replicatio: linked to cell division, anchors to membrane. Cell division: cytokinesis division of cytoplasm, mitosis division of chromosomes. Physical division of cell membrane and contents. Cell division results in two genetically identical daughter cells. Equal cell division daughter cells of same type. Unequal cell division daughter cells of different types. Mitosis is part of the cell cycle. G2 2 sister chromatids: prophase. Chromosomes align at metaphase plate: anaphase. Cell membranes partition cytoplasm: interphase again (repeat) Spindle apparatus: provides scaffold, generates force, chromatid separation, centrosomes or mtocs, asters, spindle fibers, kineticores. Phases of the cell cycle: g1, s (dna synthesis, g2, m (mitosis) Cytoplasmic determinants: factors regulating cell cycle. Checkpoints: cell cycle stopping points, cytoplasmic determinants.