BSCI 207 Lecture Notes - Lecture 30: Olfactory Receptor, Electrochemical Gradient, Membrane Potential

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Hair cells in ear and skin, photoreceptors, olfactory receptor, taste buds and more. Sensory cells receive signals and convert it into a neural output: neural output is proportional to the magnitude of the input. Not all sensory neurons send action potentials: hearing and vision neurons do not send action potentials, these neurons lack voltage gated ion channels, still have calcium ion channels to release neurotransmitters. Instead, stimulus results in a proportional change in membrane potential: resting state of a sensory neuron may still result in the release of neurotransmitter, this proportional change increases sensitivity and resolution of the associated sense. If the receptor cell does not make action potentials, the post-synaptic neuron will make one. Receptors and ion channels are coupled in different ways. Ionotropic: the ion channel is the receptor itself. It is opened by mechanical pressure or by binding a ligand. Metabotropic: the stimulus binds to the receptor molecule and actuates a g protein.

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