KNES 385 Lecture Notes - Lecture 23: Vestibular Nuclei, Brainstem, Fastigial Nucleus
21 Nov 2016
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The roles of the cerebellum and basal ganglia in motor control. Movement initiation and completion (can terminate movement) Scales movement parameters (power, speed, direction, amplitude) Adds sequencing information: sequences together multiple components. Rpe the higher the score, the worse the condition. Symptoms typically include diminished facial expressions, lack of associated movements, difficulty initiating and terminating movement, tremor, bradykinesia, hypometria (reduced amplitude), etc: slowing of movement, reduced ability to complete movement efficiently, hypokinetic movement disorder. Decrease in neurons that use dopamine as a neurotransmitter: reason is unknown. Degeneration of neurons that project from caudate/putamen to gpe. Symptoms include alteration in mood, increased irritability, suspiciousness, deficits in memory and attention, presence of rapid/jerky movements: these are typically involuntary and may involve an entire limb or simply the fingers, hyperkinetic movement disorder. Cerebellar outputs: cerebellar cortex deep cerebellar nuclei parts of brain. Cerebro-cerebellum dentate nucleus premotor cortex. Spino-cerebellum interposed and fastigial nuclei motor (motor planning) Dentate nucleus deep nuclei cortex and brainstem (execution)
