BIL 150 Lecture Notes - Lecture 5: Isoelectric Point, Ovalbumin, Alpha And Beta Carbon
26 Nov 2017
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Document Summary
A species specific polymer of amino acids with biological activity. Storage- ovalbumin (egg), ferretin (iron), casein (milk) Contractile- contract, change shape, make up elements of the cytoskeleton and muscles (actin, myosin) Structural- provide support (collagen of tendons, elastin of ligaments, keratin of hair) Receptor- respond to chemical stimuli (receptors, transcription factor, enhancers) Simple proteins- release only amino acids in acid hydrolysis. Complex proteins- made of amino acids an some other macromolecule. Glycoproteins (+carbs) , nucleoproteins(+nucleic acids), lipoproteins (+lipids) Polymers of amino acids with biological activity. 11 aa synthesized naturally by the body. 9 aa (cid:373)ust (cid:271)e i(cid:374)gested th(cid:396)ough the diet (cid:894)esse(cid:374)tial aa"s(cid:895) 2 functional groups: carboxyl (-cooh) and amino group (-nh2) These groups are ionized at physiological ph. Zwitterion- when a molecule has 2 functional groups of opposite charges. Isoelectric point: ph where there is no net charge in the molecule. Pk- ph at which all the groups are at 50% ionized an 50% non-ionized.
