BMB 401 Lecture Notes - Lecture 1: Hydrophile, Osmosis, Acid Dissociation Constant

• School: University of Miami
• Department: Biochemistry and Molecular Biology
• Course: BMB 401
• Professor: Farooq

Document Summary

U = (cid:395) w where w stands for the work done and q is the heat added/exchanged. This corresponds to the 1st law of thermodynamics which states energy is not created or destroyed but only conserved and exchanged. 2nd la(cid:449) = (cid:374)atu(cid:396)al p(cid:396)o(cid:272)esses a(cid:396)e spo(cid:374)ta(cid:374)eous a(cid:374)d lead to a(cid:374) i(cid:374)(cid:272)(cid:396)ease i(cid:374) e(cid:374)t(cid:396)opy (cid:894) s > 0(cid:895) Depe(cid:374)di(cid:374)g o(cid:374) the (cid:272)o(cid:374)ditio(cid:374)s, (cid:271)oth h a(cid:374)d s (cid:272)a(cid:374) affe(cid:272)t the spo(cid:374)ta(cid:374)eity of a p(cid:396)o(cid:272)ess. G < 0 as this (cid:272)o(cid:396)(cid:396)espo(cid:374)ds (cid:449)ith (cid:271)iologi(cid:272)al p(cid:396)o(cid:272)esses. If (cid:271)oth h a(cid:374)d s a(cid:396)e +, the p(cid:396)o(cid:272)ess is e(cid:374)t(cid:396)opi(cid:272)ally (cid:272)o(cid:374)t(cid:396)olled a(cid:374)d spo(cid:374)ta(cid:374)eous at all te(cid:373)ps a(cid:271)o(cid:448)e t = h/vs. If (cid:271)oth a(cid:396)e (cid:374)egati(cid:448)e, it is spo(cid:374)ta(cid:374)eous at all te(cid:373)ps (cid:271)elo(cid:449) t = h/ s. If h is a(cid:374)d s +, spo(cid:374)ta(cid:374)eous at all te(cid:373)ps a(cid:374)d the reverse is non spontaneous at all te(cid:373)ps si(cid:374)(cid:272)e it (cid:449)ould(cid:374)"t gi(cid:448)e us a g. F(cid:396)ee e(cid:374)e(cid:396)gy (cid:272)ha(cid:374)ge is 0 (cid:894) g = 0(cid:895) G = g - rtlnkd where kd = [a][b]/[c]