MIC 323 Lecture Notes - Lecture 17: Biome, Apicomplexan Life Cycle, Acanthamoeba

• School: University of Miami
• Department: Microbiology and Immunology
• Course: MIC 323
• Professor: Schesser Kurt

Document Summary

Inflammation in the eye: finding that organisms inside the gut educate and activate some t cells which travel between eye and gut, people with ibd often have eye diseases because the t cells interact cause these. T cells get activated and then eventually travel to eye: everything has its own microbiome. Lecture 17: fou(cid:374)d out it"s (cid:374)ot the (cid:449)or(cid:373) (cid:272)ausi(cid:374)g disease si(cid:374)(cid:272)e (cid:449)he(cid:374) (cid:449)e ga(cid:448)e a(cid:374)ti(cid:271)ioti(cid:272)s they recovered. It is the bacteria the worm carries that causes the blindness so no need to eradicate worm, just eradicate part of microbiome using tetracyclines (attack small 30s part of ribosome) 22 acanthamoeba: grazes on microbial communities in soil or water interfaces but can also cause human disease, exists in 2 forms: Trophozoite is feeding form and they eat gram stuff. Cyst form for survival: spikes on surface are for grabbing food by trophozoite, cyst can last up to 25 years, cannot kill them.