MIC 323 Lecture Notes - Lecture 22: Interferon Gamma, Complex Differential Form, Quorum Sensing
16 Dec 2016
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Camps work by binding lps and gain access to periplasm and disrupt inner membrane leading to death of bacterium. 5/6: like charge more than neutral charges of our own, amphipathic membranes with different charge on each side. 14: after initial binding there is flipping of hydrophobic side flipping to interior region of membrane. When occurs in localized area forms a pore and disrupts permeability barrier: gram , can eat anything organic, with functioning immune system we should never suffer from this pathogen cause our immune system has figured it out. Opportunistic pathogen because found in individuals that are immunocompromised. Incredible model: see the 34 individuals and they follow 10 clones they found in multiple individuals, found individuals that had same clones were going to the same clinic! (epidemiology) 28: pseudomonas does something additional with its quorum sensing. Ifn gamma was acting like an ai to increase expression of quorum sensing target.
