PSIO 303A Lecture Notes - Lecture 38: Citric Acid Cycle, Atp Synthase, Oxidative Phosphorylation

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Block 3 - lecture 8 - mitochondria 1. Know the structure of the mitochondria - inner and outer membrane, and cristae. Know that it generates nadh (required for the electron transport chain) Understand the basic concept of chemiosmotic coupling and electron transport chain. Recognize the importance of mitochondrial (electrical) potential and proton gradient and where they occur. Understand in relative terms how much more atp is generated by oxidative metabolism vs. glycolysis. Structure of the mitochondria play a big role in its function. Inner membrane = folded so that parts project inward (folds = cristae mitochondriales) Molecules that are part of the electron transport chain. Contains enzymes required for oxidation of pyruvate and fatty acids, and for the citric acid cycle. Has its own dna (mtdna), special mitochondrial ribosomes, trna, and enzymes required for the expression of mitochondrial genes (stuff that looks like if the mitochondria is almost its own independent cell).

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