CHEM 4041 Lecture Notes - Lecture 2: Glycomics, Furan, Maltose
Document Summary
Mass spec and isotopes are very important for biochemistry. Glycomics - the study of the glycome, all of the carbohydrates and carbohydrate- associated molecules that cells produce. Osmotic balance - glucose can not be stored in its normal form because high concentrations cause cell death (disturb osmotic balance). Instead it is stored as units in a large polymer, which is not osmotically active. Transferases - complex carbohydrates are synthesized through the action of speci c enzymes, glycosyltranferases, which catalyze the formation of glycosidic bonds. Many different enzymes are required because of diversirt of glycosidic linkages. Glycosyltranferases account for 1-2% of gene products in all organisms examined. Epo - it is a vital hormone. dramatically improved treatment for anemia (especially induced by chemotherapy), secreted by the kindest and stimulates production of. Mucopolysaccharidoses (group of diseases) resulting for the inability to degrade glycodsminoglycans. Purpose of previous is to show the importance of sugars! Aldehydes can react with alcohols to form hemiacetals.
