BIO 479 Lecture Notes - Lecture 4: Anterior Pituitary, Posterior Pituitary, Intracrine

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All neuromodulators are neurotransmi(cid:130)ers, but not vice versa. Neurosecretory cells - produce neurohormones (cid:336)or neurosecre(cid:2210)ons(cid:337) Posterior = axons extend into pituitary gland. Triggered by s(cid:2210)mulus, ac(cid:2210)on poten(cid:2210)al triggers neurohormones to form then be released. Anterior = axons do not extend into pituitary. Can form nuclei in nervous system (cid:336)cns(cid:337) Are in clumps or tracts in nervous (cid:2210)ssue. Product made in cell bodies and stored at the end of the exon. Products not dumped directly into blood stream. Middle man = instead, pituitary cells and local blood vessel help products travel and dump into bloodstream. From presynap(cid:2210)c neurons (cid:336)neurotransmi(cid:130)ers(cid:337) and neurosecretory cells are made in soma (cid:336)cell body(cid:337) and packed in transport vesicles. Stored in vesicles at the terminal knob. Released in response to an ac(cid:2210)on poten(cid:2210)al. Usually epithelial in origin (cid:336)no axons, terminal knobs, synapses, etc. (cid:337) Have signals that travel via ecf or circulatory system (cid:336)portal or general(cid:337) Can be arranged in folded sheets or cords