NUR 416 Lecture Notes - Lecture 8: Exocrine Gland, Cystic Fibrosis, Mucus
Document Summary
Multi-system disease characterized by exocrine gland dysfunction. Autosomal recessive inheritance: transmembrane regulator (cftr) protein is absent, insufficient or mutated, ctfr protein. Ion channel protein that moves chloride ions from inside cell to outside cell. Once the chloride ions are outside the cell, they attract a layer of water. Water layer is important because it allows cilia to sweep back & forth moving mucus up & out of the airways. Exocrine glands: secretions released through ducts onto an organ"s surface, ducts. Endocrine glands: release hormones directly into the bloodstream. Lungs: thick, sticky mucous buildup, bacterial infection, widened airways, blood in mucous, most prominent & severely affected area. Skin: sweat glands produce salty sweat. Cannot impregnate a women because cannot release semen: female complications. Meconium ileus: newborn small intestine plugged with thick, tenacious meconium. Steatorrhea: fatty stools d/t impaired fat digestions. Rectal prolapse: secondary to intestinal obstruction & impacted feces. Failure to thrive: aren"t absorbing nutrients they need.