BIO 112 Lecture Notes - Lecture 15: Release Factor, Spliceosome, Repressor

• School: University of Rochester
• Department: Biology
• Course: BIO 112
• Professor: Ingrid L.Stefanovic

Document Summary

Recognition and attachment of correct amino acid depends on the enzymes called. Aminoacyl-trna synthetases which covalently bond each amino acid with the appropriate set of trna molecules. This reaction attaches the amino acid to the 3" end of the trna and requires hydrolysis of atp. An error in either step would cause the wrong amino acid to be incorporated into a protein chain. In the sequence of events shown, the amino acid tryptophan (trp) is selected by the codon. Form peptide chain from the formation of a peptide bond between the carboxyl group at the end of a growing polypeptide chain and a free amino group on an incoming amino acid. Proteins are synthesized from the n-terminal end to the c-terminal end. In this way, each amino acid added carries with it the activation energy for the addition of the next amino acid rather than the energy for its own addition.