BIO 198 Lecture Notes - Lecture 38: Lysogenic Cycle, Antitermination, Ciii-Dt

11 views8 pages

Document Summary

N protein transcribed from promoter left and n protein allows extension of transcription beyond termination sequences of tl, tr1 and tr2. Termination left produces ciii mrna and ciii protein. Termination right 1 produces cii mrna and cii protein. Accumulation of ciii and cii complex leads to lysogenic cycle. Ciii/cii complex binds to promoter left and allows transcription of integrase for prophage integration lysogenic cycle. Ciii/cii complex binds to promoter repressor expression to transcription of ci which is the lambda. Lambda repressor protein is the c-n c-n dimer molecule. Lambda repressor protein binds to or1 and or2 and starts transcription from promoter repressor. -------cii protein is sensitive to bacteria proteases that are present when host cell is growing well so. Cii will be degraded and wont be able to from ciii cii complex and so wont be able to bind to pl and. Pre for integrase and ci or lambda repressor protein.