PSYCH 202 Lecture Notes - Lecture 4: Nitric Oxide, Raphe Nuclei, Atypical Antipsychotic
Document Summary
Raphe nuclei -cortex, hippocampus, basal ganglia, -arousal, mood, sex, thalamus, hypothalamus, cerebellum appetite, sleep, pain, spinal cord regulation. Drugs that affect this nt system: antidepressants, lsd, dmt, psilocybin, mdma, Throughout the brain -throughout the brain -excitation . Drugs that affect this nt system: alcohol (antagonist: blocks effects of glutamate), phencyclidine (aka pcp/angel dust), ketamine, atypical antipsychotics. Throughout the brain -throughout the brain -inhibition . Drugs that affect this nt system: antianxiolytics (increase gaba and reduce anxiety), (increase gaba to balance glutamate activity - epilepsy), alcohol, ghb barbiturates (potent sleeping drugs), benzodiazepines, anticonvulsants. Hypothalamus & -periaqueductal gray area -analgesia . brainstem -nucleus accumbens -pleasure . Drugs that affect this nt system: opiates (opium, morphine, narcotics), naloxone, naltrexone. Postsynaptic membrane -inside the presynaptic membrane -moderates nt release. Receptors: none - crosses the membrane and activates second messengers. Cell bodies making it axon terminals release it at functions . Postsynaptic membrane -presynaptic receptors -mood, perception, memory formation, sedation, anxiety regulation analgesia, appetite,
