PSYCH 202 Lecture Notes - Lecture 2: Resting Potential, Schwann Cell, Membrane Potential

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Responsible for edema (retention of water - swelling, which causes pressure that can kill neural cells) Permanent glial scarring in spinal cord injuries = axons cannot regenerate to carry sensory/motor information to muscles = paralysis. When you experience some injury to the brain or bacteria in brain, microglial into the area -- microglial fights bacteria/virus and digest it. (cid:1441)clean-up team(cid:1442): find and digest debris in brain. Do the same thing, source of myelin. Autoimmune disease: own immune disease targeting set of cells in body that are misrecognized as foreign. specifically, myelin are misrecognized and attacked. Lose insulation around axons electrical impulse cannot travel down axon. Negatively charged particles on inside of cell, positive charged ions on outside. Outside of cell: sodium ions and chloride ions (high concentration), potassium ions (low concentration) Inside of cell: high concentration of potassium. Organic anions (negatively charged proteins) - do not leave membrane and keep things negative at rest.

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