PSYCH 202 Lecture Notes - Lecture 24: Adrenocorticotropic Hormone, Striatum, Amygdala
Document Summary
Hpa axis: hypothalamus -> pituitary -> adrenal, crh, corticotropic releasing hormone, detected by cells in the pituitary and releases acth (adrenocorticotropic hormone, pituitary gland. Adrenal gland -> cortisol released: h tells p (via crh, produce and secrete acth, which tells a to secrete cortisol, generally inhibits its own release, as you get more cortisol, you down regulating signals to release more cortisol. Long-term stress -> a lot of issues (immune [autoimmune disorders], intestinal [gastrointestinal disease], etc. ) Slower (takes longer for cortisol to be released: adrenal glands secrete glucocorticoid hormones such as cortisol, prolonged effects all over body and brain. "muscles: have some glucose!" and "long-term systems (immune, digestive, reproductive): take a break. " Chronic stress and dendrites: chronic stress causes frontostriatal reorganization and affects decision-making, greater and longer "habit-driven" striatum dendrites in stress rats vs. control rats (more similar to. Fewer and shorter pfc dendrites in stress rats vs. control rats.
