ANS 1 Lecture Notes - Lecture 8: Specific-Pathogen-Free, House Mouse, Knockout Mouse
Document Summary
First started dissecting animals and wrote down and recorded what he witnessed. Saln - polio vaccine - tested on rhesus mac (monkey) - used for all kinds of research. Ucd = largest school that uses animals. Institute for laboratory animal research (ilar: dictate appropriate use o. Iacuc (institutional animal care and use committee) - law. Scientists (some do research on animals, some don"t) Universities, government, business -> controlled by iacuc: only covers certain species. Std farm animals -> not covered because they are not research animals, they are farm animals. 3000 years ago: pets, agury (tell the future from the insides - guts) Secretive, burrowing: used to be associated with disease, poverty, generally dark things (some element of bad) Eat seeds -> bad because they eat our seeds: now -> think of mice as whimsy, genetics -> underlying element in research. Eliminate source of variability with genes -> genetically identical.
