ANT 1 Lecture Notes - Lecture 5: Mendelian Inheritance, Genotype Frequency, Allele Frequency

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Lecture 5: population genetics: populations genetics the study of processes that change gene frequencies within populations. Step 1: compute the frequency of alleles in gametes: meiosis each gamete carries only one allele (haploid) so. Step 2: compute the change that a given pair of alleles meet. Step 3: compute the frequency of alleles in the next generation: random mating changes genotype frequencies, but not allele frequencies. The frequency of genotypes has changed from f0 to f1 generation: : after one generation of random mating, genotype frequencies remain constant, hardy-weinberg equilibrium p2 + 2pq + q2 = 1. The hardy-weinberg relationship describes the consequences of sexual reproduction and random mating on allele and genotype frequencies. If everything else is equal, allele frequencies don"t change (variation is maintained in the population): after one generation of random mating, an equilibrium value for genotype frequencies is reached genotype frequencies stay constant.

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