ANT 1 Lecture Notes - Lecture 11: Alternative Splicing, Intron, Neutral Theory Of Molecular Evolution
Document Summary
Variation within groups decreases with distance from east africa. Genetic distance: a measure of how different two groups are. Total variation, sep. within group variation -> b/w group variation. Relationship between genetic distance (based on strs) & geographic distance. Within-region genetic variation decreases with distance from africa. Genetic distances between human groups increase w/ geographic distance. Selection would show up as more non-synonymous mutations relative to synonymous ones or ones that would affect the phenotype. Cause regions near selected loci to be less variable. Regions closer to selected locus expected to be less variable. Humans have so little genetic variation relative to great apes. A: human population was smaller fairly recently in the past. All humans originate recently from small african population. Within group human variation decreases with distance from africa. A: groups further from africa were the product of more founding events and were founded more recently (bottleneck)
