BIS 2B Lecture Notes - Lecture 11: Mendelian Inheritance, Allele Frequency, Tyrosinase

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Yes, most traits are polygenic with environ effects on expression. Nilsson-ehle (1909): effects of multiple loci on wheat chaff color. 3 loci (a, b, a), each with 2 alleles (a", b", c"), each contributes equally to color of chaff. When large enough number of genes influence a character, will have continuous, normal frequency distribution continuous variation = bell curve model. Did not observe his independent 25% per allele combination. Was close, but instead observed 41, 42, 9, and 8% distribution started mapping how far apart traits were by the frequency of crossovers linked traits vs. recombinants. Dunno what chromosomes or cell divisions are doing, infer a process traits on chromosomes, low frequency of crossover (cross, clip, segregate) where a part of chromosome 1 clips and latches onto chromosome 2, and vice versa = recombination. What is a population? same species interbreeding. Nat select acts on individual, but now we move to characterizing the population population genetics.

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