MCB 10 Lecture Notes - Lecture 7: X-Inactivation, Barr Body, Allele
19 Nov 2016
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Document Summary
Is the set of dna sequences inherited on one chromosome due to linkage disequilibrium: make it possible to track specific chromosome segments in pedigrees. Disruptions of a marker sequence indicate crossover sites: using trios to estimate recombination rates. % recomb = (n(rm) + r (rf) )/n(chrom) Sex chromosomes determine gender: human males are the heterogametic sex with different sex chromosomes (xy, human females are the homogametic sex (xx) In other species, sex can be determined in many ways. For example, in birds and snakes males are homogametic while females. Sex determination are heterogametic: during the fifth week of prenatal development, all embryos develop two sets of. Reproductive ducts mullerian (female specific) and wolffian (male specific: an embryo develops as a male or female based on the absence or presence of the y chromosome. Specifically the sry gene (sex- determining region of the y chromosome) X and y chromosomes: x chromosome. Acts as a homolog to y in males: y chromosome.
