NPB 10 Lecture Notes - Lecture 8: Stretch Reflex, Cerebellum, Primary Motor Cortex
23 Jan 2018
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Contraction contractile fibers (thick filaments and thin filaments) slide next to e/o. In a rested muscle (not contracting), the filaments are not sliding: signal for contraction comes from a motor neuron. Ap induces to release acetylcholine: ach binds to its receptor on the muscle cell, muscle cell has an ap. The ap in muscle cell causes calcium ions (ca2+) to go onto the cytoplasm of muscle cell: the ser stores the calcium ions. When the ca2+ inside the cells increase signal to contract. Ca2+ interact with regulatory protein that block the thin filaments. Requires atp provides energy and heads can unbind the thin filaments. Coordinates motor activities and also helps us smooth our muscle activities: cerebral cortex motor cortex, primary motor cortex, pre-frontal associative cortex. Involuntary controlled muscle: cardiac muscle found in the heart; has striated/striped appearance, smooth muscle no apparent striped look to it; has thick and thin filaments, but not arranged as sarcomere.
