NUT 10 Lecture Notes - Lecture 12: Coeliac Disease, Blood Sugar, Insulin Resistance

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10 Aug 2018
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Basic currency of carbs in bloodstream: 6-carbon sugar glucose. Hormone insulin: needed for glucose entry into cell. Made by pancreas (same as digestive enzymes) Insulin like a hall monitor to body cell, glucose as students. Blood glucose level below 100 if healthy, rises while eating, brought down by insulin. Absence of glucose (like t1 diabetes) = glucose accumulates outside of cell, cell starving. Insulin resistance (t2 diabetes) = receptor & action of insulin not working. Blood sugar level at 120-130, goes up to 200 when eating. Q: insulin resistance is a problem because it causes. Blood glucose levels to rise above normal. Damage to artery walls/blood vessels due to elevated glucose, leads to cardiovascular disease. Glycogen = storage form of carbohydrate, found in muscles & liver. Energy out of 6-carbon ring into two 3-carbon units - anaerobic (without oxygen) energy metabolism. Used by brain & nerves, and muscles during high intensity exercise.

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