PSC 101 Lecture Notes - Lecture 5: Tryptophan, Serotonergic, Dopamine Receptor
28 Aug 2018
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Quiz questions, the most common fixative of nerve tissue is: In the presence of enzyme chat, an acetate from acetyl coenzyme a is transferred to a choline molecule making ach: breakdown of ach. In the presence of enzyme acetylcholinesterase ach can be broken down into acetate and choline: ach receptor subtypes, nicotinic: most are ionotropic and excitatory, neurotransmitter binds directly to channel, channel opens immediately. Sodium ion channel: methylphenidate blocks dopamine and norepinephrine transporters, amphetamines (meth, alter dopamine transmission in 2 ways, enters neuron by passing directly through nerve cell membranes. In axon terminals methamphetamine enters the dopamine/norepinephrine containing vesicles and causes the release of the neurotransmitter. In synapse amphetamines block da and ne transporters: can even run transporters in reverse releasing more neurotransmitter into the synapse, dopamine receptor subtypes, all dopamine receptors are metabotropic, d1-like family (d1 and d5 receptors) Stimulation of receptor increases camp: d2-like family (d2, d3, d4 receptors)
