PSC 126 Lecture Notes - Lecture 4: Semiconservative Replication, Primase, Telomere
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Guide - chapter 5 & 16 dna structure and replicatoin. Describe the methods and results for each of the following experiments. Explain how each provided evidence that dna is the genetic material, not protein. * meselson and stahl nitrogen isotope incorporation into bacterial dna. Describe the structure of dna and rna, including the importance of hydrogen bonds in. Des(cid:272)(cid:396)i(cid:271)e how cha(cid:396)gaff"s a(cid:374)alyses of the ratio of nitrogenous bases in dna helped to confirm the structure of dna. Explain how research with bacteria and different isotopes of nitrogen provided evidence that dna replication occurs by semiconservative replication. Describe the basic process of dna replication; including the importance of a template strand, complementary base pairing, dna primase, and dna polymerase. Describe what mutations are, and what can increase their likelihood. Explain the usefulness of studying dna and mutations in order to evaluate the closeness of different species. Describe what telomeres are and their hypothesized importance to eukaryotes.
