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Lecture 8

PSC 130 Lecture Notes - Lecture 8: Selective Serotonin Reuptake Inhibitor, Anxiety Disorder, Brenda Milner

Course Code
PSC 130

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February 9, 2017:
I. Recognition Memory and Stress Effects on Memory
A. Testing Explicit Memory
1. Recognition identification of information from previous encounters or knowledge
2. Recall generating information from previous encounters or knowledge
B. Processes Supporting Explicit Memory
1. Predicted ROCS a way to plot memory performance
a. Threshold (Recollection)
i. Either you remember or you don’t (no in
b. Signal Detection (Familiarity)
i. Some memory; a symmetrical curve
ii. Involves different levels of confidence
2. Recognition = Recollection + Familiarity
a. Predicted ROCs: curve is asymmetrical
b. Observed ROC
i. Confidence judgements
ii. Measured by familiarity curve is above
chance (diagonal line)
C. Stress
1. What is stress?
a. It used to be a way to describe a physical force that an object and withhold
b. Not used to refer to a mental state of mind until 1950s
2. Stress (response) a set of responses that typically involves an unpleasant state (Hans Selye)
a. Occurs when we perceive that available resources are insufficient to meet the demands of a
3. Stressor a stimulus that is perceived as threatening or demanding, and produces stress
a. Positive Stressors (Eustress) vs Negative Stressors (Distress)
i. Both put strain on the body and brain
4. Laboratory Stressors
a. Physical: Cold-Pressor Test (CPT)
i. Stresses cardiac system for body trying to maintain body heat
b. Psychological: Trier Social Stress Test (TSST)
i. Simulate an interview; perceive the situation as stress
5. Stress Physiology Activation of Sympathetic Nervous System and
HPA Axis
a. Sympathetic Nervous System (fast)
i. Releases epinephrine and norepinephrine
ii. Affects the brain
b. HPA axis (slow takes up to ½ hour to take effect)
i. Hypothalamic signal from brain region, sends
signal to pituitary
ii. Pituitary sends signal to adrenal
iii. Adrenal releases cortisol that binds to neurons
c. *A “cascade” of events starting in the brain, but reaching all of the body
D. Memory in the Brain
1. Henry Molaison (HM)
a. Hippocampi removed (and some more cortical regions)
2. When HM’s hippocampi was removed,
a. Impaired: new learning
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