BIO SCI 37 Lecture Notes - Lecture 10: Lewy Body, Vascular Dementia, Motor Disorder
23 Sep 2016
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Document Summary
Specific disorders (focal damage) - someone falls and hits their head; particular piece of brain injured, happens in strokes, traumatic brain injury. it"s a brain wound (like hurting your arm). Generalized disorders - widespread damage like dementia, neurodegenerative disorder; brain atrophy & gets smaller and smaller as a function of time; multiple sclerosis (demyelinating diseases) White matter tearing, squeezing neurodegenerative disorders: brain subjected to lots of degeneration. Entire brain shrinking; brain matter gets smaller and spaces get wider (mind alzehimer"s disease) Sometimes you see whle portions of brain disappearing: health intact brain dementing diseases. Dementia - clinical phenotype (not like alzheimer"s disease where it has pathological hallmarks and things u can see on brain scans) Lose cognitive capacity: memory, thinking skills, plan to execute action, learn from mistakes, personality changes, make rash decisions, childlike behavior (part of the brain that"s mature and making rational decisions degrade)
