BIO SCI 38 Lecture Notes - Lecture 25: Perirhinal Cortex, Viral Vector, Pronucleus
10 Jan 2020
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(a) during the training phase, the animal simply explores a novel environment with two identical objects present. (b) at some later test interval (minutes to hours to days), one of the objects is replaced with a novel object. Rats that have a strong memory of the experience in a will spend more time exploring the novel object. If the rat has no memory of the experience during the training phase, it will spend the same amount of time exploring each object during test. Note: this type of simple object memory does not require a functioning hippocampus system. However, successful performance of this task requires an upstream input to the hippocampus, the perirhinal cortex. The hippocampus is needed to remember context. (a) rats were allowed to explore two objects, a cube and a cylinder. Each object was explored in a different context. (b) the rats were then tested twice.
