BIO SCI 38 Lecture Notes - Lecture 29: Memory Consolidation, Neocortex, Amygdala
10 Jan 2020
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Another reason different brain regions exhibit different levels of sparsity the proportion of neurons active during experiece. The dg is very sparse (~ 1-2% of neurons active for a given 5 min experience), and ca1 is much less so (~35% of neurons active in same experience) Another reason different brain regions exhibit different levels of. Sparsity the proportion of neurons active during experiece. The dg is very sparse (~ 1-2% of neurons active for a given 5 min experience), and. Ca1 is much less so (~35% of neurons active in same experience) Determine whether molecular changes seen following ltp induction also occur in the brain after learning. Determine whether blocking molecular processes necessary for ltp also block learning or memory consolidation. Blocking insertion of ampa receptors into dendritic spines. Blocking or inhibiting key kinases such as camkii. Blocking expression of specific iegs, such as arc. There is now compelling evidence that ltp (or ltplike processes) is necessary for memory formation.
