BIO SCI 38 Lecture 40: Bio Sci 38
10 Jan 2020
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Document Summary
Memory system interactions in memory consolidation and retrieval. Started having seizures after a bicycle accident at age 7. Seizures got worse into adolescence and early adulthood. Surgery in 1953 at age 27 by neurosurgeon dr. william scoville. Bilateral resection of hippocampus and other structures of the medial temporal lobe (mtl; including amygdala and entorhinal cortices) The surgery did stop the seizures, but resulted in profound anterograde and graded retrograde amnesia for declarative memories. He was studied for decades by 100s of researchers, but most prominently. A good video of her contributions to studying hm, in her own words. 1) damage to the hippocampal formation and mtl dramatically impacted new declarative memory formation and caused a graded retrograde amnesia. Conclude: over time, the brain systems supporting declarative memory retrieval change. This time-dependent transformation of declarative memories from a hc-dependent to hc-independent form is commonly called systems memory consolidation .
