BIO SCI 47 Lecture Notes - Lecture 12: Foreign Body, Prednisone, Autonomic Nervous System
Immune System
● Cortisone and Prednisone act like glucocorticoids and suppress immune response
● Glucocorticoids drive alertness
● As you are taking medication, signal is getting sent to hypothalamus saying to shut down
adrenals
○ Negative feedback loop
○ If you shut down adrenals, they’ll shrink
■ Become less effective
● Viral infections have cortisol receptors
○ Pays attention to glucocorticoid levels bc then it knows when your system is
compromised
■ Makes it easier for this virus to get active
● Stress suppresses immune response
● Cancer cells are more active than regular cells
○ Increased release of sugar from liver, feeds cancer cells
● Prednisone treats leukemia bc leukemia is white blood cell cancer
○ Suppresses production of immune cells
Memory
● Formation of memory
● Starts with sensory input
○ Unattended information is forgot
● Attention sends an event to short term memory
○ Unrehearsed information is lost
○ When you encode information it goes to long term memory
● Retrieving is pulling memories from long term
● Declarative vs Nondeclarative memory in long term
● Psychoneuroimmunologists determine how what goes on in your head affects your
immune system
● The autonomic nervous system sends nerves into tissues that form or store the cells of
the immune system and eventually enter the circulation
○ Immune system tissue is sensitive/receptive to hormones released by pituitary
Document Summary
Cortisone and prednisone act like glucocorticoids and suppress immune response. As you are taking medication, signal is getting sent to hypothalamus saying to shut down adrenals. If you shut down adrenals, they"ll shrink. Pays attention to glucocorticoid levels bc then it knows when your system is compromised. Makes it easier for this virus to get active. Cancer cells are more active than regular cells. Increased release of sugar from liver, feeds cancer cells. Prednisone treats leukemia bc leukemia is white blood cell cancer. Attention sends an event to short term memory. When you encode information it goes to long term memory. Retrieving is pulling memories from long term. Declarative vs nondeclarative memory in long term. Psychoneuroimmunologists determine how what goes on in your head affects your immune system. The autonomic nervous system sends nerves into tissues that form or store the cells of the immune system and eventually enter the circulation.