BIO SCI 93 Lecture Notes - Lecture 4: Thymine, Prope, Uracil

• School: UC-Irvine
• Department: Biological Sciences
• Course: BIO SCI 93
• Professor: Busciglio/ Wood/ Green

Document Summary

Function support, storage, transport, signaling, receptors, movement, catalysis, defense. Protein: one or more polypeptides with speci c 3-d conformation amino acids>polypeptides>proteins. Aa are joined by dehydration reactions peptide bond (covalent) The function of a protein depends on its conformation. There are 3 levels of structure in a single polypeptide that organize the folding. Hydrogen bonding by atoms in the backbone (formed by carboxyl and amino groups in backbone) (n-h o=c) Hydrogen bonds are relatively weak interactions but when they work together, they are strong. Pleated sheets- pulls back on itself, parallel to one another. If many polypeptides are required ex: collagen ex: hemoglobin (2 beta chains and 2 alpha chains) The speci c function is an emergent property originated by the. Change from glutamic acid that can react with water to valine which is hydrophobic. Protein conformation is in uenced by the environment ph. Misfolded protein= denatured protein needs to refold properly.