BIO SCI 93 Lecture Notes - Lecture 27: Gap Junction, Electric Current, Myelin

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BIO SCI 93 Full Course Notes
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BIO SCI 93 Full Course Notes
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Speed of action potential increases with axon"s diameter. In vertebrates, axons insulated by myelin sheath: causes action potential"s speed to increase. Action potentials formed only at nodes of ranvier: gaps in myelin sheath where voltage-gated na+ channels are found. Salutatory conduction: action potentials in myelinated axon jump between nodes. Electrical current flows from one neuron to another. Chemical neurotransmitter carries information across the gap junction. Direct synaptic transmission involves binding of neurotransmitters to ligand gated ion channels in postsynaptic cell. Neurotransmitter biding causes ion channels to open: generates postsynaptic potential. Neurons talk to each other at chemical synapses using neurotransmitters. Opening of ligand gated ion channels by neurotransmitters results in postsynaptic potential. Epsps produced nearly simultaneously by different synapses on the same postsynaptic neuron add together. Combination of epsps through spatial and temporal summation can trigger an action potential. Involved in muscle stimulation, memory, formation, and learning. Available treatments focus on brain pathways that use dopamine as a neurotransmitter.

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