BIO SCI N150 Lecture 1: 1
21 Dec 2016
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Repeating cagrepeats transcribed into rna and translated into protein. Knock out mouse determined that it is not a loss of function disease. We normally have 25 cag repeats - we need this for normal function. Environment/different genetics contribute to when you get disease. Non coding region - fragile x syndrome - usually in girls. Prioin diseases are protein propagation diseases--> protein misfolding signals. Found in cannibal populatins; due to mad cow disease too. Older people have a accumulation of bad proteins that are not broken down. Neurons cannot grow forever in a dish. Make prceise copeis of themselves over and over again and differentiate. Each of us has 400 miles of blood vesels in brain - high oxygen/blood glucouse in brain. Blood supply gets blocked and brain starts to die --. cause of risk factor of alheimers disease. In addition,, to looking for heart deaseise/cardiovascular prolems to determine if it is a vasculature problems.
