BIO SCI N150 Lecture 8: 8
21 Dec 2016
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Document Summary
Hd - anticipation > 55 cagrepeats - younger onset. Ad is usually combination of amyloid plagques and tau tangles. Vascular dementia caused by the vulneratbility of brain due to blood circulation problems / need to get energy and oxygen to brain. Specific genes that stem cells that allow them to divide and reprogrammable. If you put ips cells, youll get brain tumors. Multipotent - already partly differentiated - one type may differentiate into any kind of neuron. Cost of ad over the years will cost a lot more in the future. Population of adwill increase because a lot of people live over 85. Progressive - once symptoms initiate, progression of loss of neurons occurs. Starts with memory and goes to other body functions (movements, visualspatial ability). Need an informant (someone who sees them frequently) Amnestic subtype (loss of memory due to shock, brain injuyry,lose a chunk/block of memories) most likely develop into ad.
