PUBHLTH 120 Lecture 9: Lecture 2 Chapter 2

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The study of the distribution and determinants of disease in human populations : objective: to examine relationship between an exposure and a health outcome. Generates data on nutrition and health outcomes in populations through observational studies and experimental trials. (p 6) Case study: using nutritional epidemiology to study the mediterranean diet and cardiovascular disease. Cardiovascular disease: any of the diseases affecting the heart and blood vessels. Ischemic heart disease/coronary heart disease (plaque build up in blood vessels that supply oxygen to heart) Peripheral artery disease (plaque build up in arteries that supply oxygen to head, organs and limbs) Stroke (blood supply to part of brain is interrupted or severely reduced causing damage to brain)-3rd leading cause of death in us. Hypertension (high blood pressure > 140 mm hg systolic/90 mm hg diastolic) Leading cause of death worldwide, 30% of total deaths. Phosphorus, calcium, magnesium, flavonoid inversely associated with bp. Vit d supplementation lowers bp in hypertensive patients.

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