CHM 2211 Lecture Notes - Lecture 3: Reaction Rate, Stereochemistry, Addition Reaction
Document Summary
As temperature increases, amount of 1,4 product increases. Rules of the diels-alder reaction: the diene can react only when it adopts de s-cis conformation, cis orientation is more reactive than trans orientation, diene should be in cis or s-cis conformation. If it is in s-trans conformation, the diene rotates into a s-cis conformation: electron-withdrawing substituents in the dienophile increases the reaction rate, the stereochemistry of the dienophile is retained. If diene is cis, product will be cis. We will only have one or the other product, not both cis products.
