HSC 3211 Lecture Notes - Lecture 4: Vaccine Adverse Event Reporting System, Hepatitis B Vaccine, Hepatitis B Immune Globulin
Document Summary
Cdc immunization prevents between 2 and 3 million deaths every year. Without vaccines, global eradication of smallpox, and elimination of poliomyelitis and measles from large parts of the world would have been impossible. World immunization week begins april 24th (cdc, partners, and countries around the globe) Aim promote one of world"s most powerful tools for health vaccines to protect, or immunize people of all ages against disease. Circulating antibodies of organism that provide protection against infectious disease. Newborns: maternal antibodies transferred through placenta and then through breast milk. Recent hbv exposure and not immunized with hbv vaccine: human immune globulin (ig) confers passive immunity. Emergency: specific antitoxins confer passive immunity (diphtheria antitoxin, trivalent botulinum antitoxin) Longer lasting (sometimes lifetime), rapidly stimulated immunity in cases of re- exposure to some/closely related antigens. **many antigens are being prepared in acellular (cell-free) media to reduce risk of negative side effects.
