GE CLST 73A Lecture Notes - Lecture 5: Sodium Channel, Facilitated Diffusion, Rectifier

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**moore 100 mid term location be there at 6:50*** A rapid dramatic change in voltage across the membrane. We have action potentials in order to : communicate with other neurons, synaptic potentials are generated from somas, synaptic potentials decay over distance therefore cant get you long distance communication. Theoretical voltage would be the equilibrium potential of the cell if ions were to allow to flow across the electrochemical gradients without facilitated diffusion. E value with a cation with high concentration outside, low in. If eion is +20 the ion with go to plus 20 but no higher, concentration gradient determines. E value (voltage) e values is the theoretical voltage. When you depolarize the cell, more channels open and more current flows in. If you reduced the sodium concentration, the amplitude would be less because it would take less to counter balance. The theoretical e value is more positive. Sodium channels: voltage dependence and time dependence. (inactivation)

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