HIST 3D Lecture Notes - Lecture 15: Methylene Blue, Antigen, Syphilis
Document Summary
Anti-bacteria: antibiotic: kill/limit the growth of bacterial pathogen, bacterial antagonism. Bacterial was seen as the main category of the cause of human disease. Learn how to culture and identify them in large culture. Growth of one species would inhibit or kill other bacteria in the same culture: the e ect of bacterial antagonism, if you had a mix culture, then penicillin kill others, 1890s pyocyanase. Encouraged doctors to try out the use of the substance. Turned out: e cacy was seen not as much / decreasing, side and lethal e ects, ehrlich"s life. Developed stains: methylene blue: ehrlich"s concept. Many important reaction are based upon the tting together of molecules. Lock and key: the complex of antigen and antibody would no longer be activate. Looking for unusual disease: trypanosomiasis: sleeping sickness, support the imperial expansion of his country, an indigenous disease lethal for the whites, the compound atoxyl had some activity against trypanosome.
