LIFESCI 2 Lecture Notes - Lecture 9: Cyanide Poisoning, Atp Synthase, Electron Transport Chain
Document Summary
Energy in glucose is used to make atp. Electron transport chain: final collection of energy from nadh/fadh. H+ move with concentration gradient to atp synthesis. The movement of protons from high to low concentration. Not formation because formation of bonds is an endergonic, anabolic reaction. Not electrons because h+ has no electrons and h+ are directly used for the synthesis of atp. They are recycled to be used as temporary storage again. The electrons move down each shuttle because the electron affinity keeping increases. The more positive the redox potential, the more difficult it is to remove electrons. A) a drug that increases rate of diffusion (leakage) of protons across the inner mitochondrial membrane. Wrong because leakage means that the protons are going through the lipid bilayer and bypassing the shuttles. B) a drug that increases the ph of inner mitochondrial matrix. Electron affinity is no longer greater, electrons cannot move any more.
