LIFESCI 2 Lecture Notes - Lecture 20: Natural Killer Cell, Extracellular Fluid, Innate Immune System
14 Sep 2016
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Document Summary
Antigens anything that can illicit an immune response. Autoimmune disease body attacks its own cells. Granulocytes (endomemebrane system gets stained) involved in inflammatory response. Eosinophils attack parasites e. g. worms, unicellular amoeba. Neutrophils/phagocyte (70%) indiscriminately kill cells and they die. Monocytes/macrophages (phagocytotic) big, engulf microorganisms and digest. Antigen-presenting cells (putting antigens on their surface e. g. mhg ii). Release cytokines (chemicals that carry out immune functions) Recovers interstitial fluids and returns it to the circulatory system. Difference between circulatory and lymphatic: lymphatic is a one-way system. Picks up interstitial fluid forming lymph by osmosis. Transport by pressure to the cervical and back to the blood. Bone marrow where all white blood cells are made and red blood cells formed. Distinguish within adaptive immunity between cell and humoral mediated immunity. Antibodies (immunoglobulins) proteins produced by b cells. They target particular antigens on the surface of pathogens and mark pathogens for destruction. One gene many proteins because of exons and introns.
