LIFESCI 7C Lecture 1: LS 7C Week 1 Monday Lecture

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15 Feb 2019
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Cells need to communicate with each other, based on molecular interaction. Cell communication is important because it is integral in achieving homeostasis. If atp is too high, then pfk is inhibited and less atp is made. If atp is too low then pfk is activated and more atp is made. Glucose is a source of atp, so there needs to be a normal level of it. Receptor is either located on the plasma membrane or in the cytoplasm. Types of signaling molecules: estradiol, epinephrine, glucagon (most signaling molecules are hormones), cortisone. Diffusion happens if the cell is small and/ or nonpolar, (is it water soluble or non water soluble?) Cell surface receptors are on the plasma membrane. Intracellular receptors pass into the cell and bind in the cytosol. Step 4 is termination: turns off process, also known as phosphorylation. Gene protein receptor only work is it binds to a gcpr receptor.

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